Clinical - Graphs
HYDRATION
THE TEST
To test the effectiveness of moisture retention, products are applied to the skin model, and moisture levels are measured at 10 minutes, 6 hours and 24 hours post-application. The probe used in testing measures moisture levels 0.5mm below the surface of skin to give a true representation of the hydration levels products provide to the epidermis.
THE RESULTS
All Plantkos® formulas were proven to maintain higher moisture levels compared to untreated skin, and were more effective than the industry-standard moisturizing cream used for comparison. For each of our products, higher moisture levels were seen immediately in the first 10 minute testing interval, and remained significantly higher up to 24 hours post application when compared to the baseline.
MICROBIOME
THE TEST
To test product effects on the microbiome, the skin models are seeded with a mix of C.acnes, C.striatum, and S.epidermis, which are allowed to establish on the outer most layer of skin, the stratum corneum. Products are applied, then the model is incubated for 24 hours at controlled temperature, after which biopsy samples are taken and tested individually.
THE RESULTS
All four of our formulas designed to protect and maintain the microbiome after cleansing - our Eye Cream, Face Mist, Triple C Serum and Face Lotion - were Certified Microbiome Friendly. Each product was shown to support and maintain the health of the microbiome.
BARRIER FUNCTION
THE TEST
Our skin barrier testing has two metrics - the ability of formulas to activate genes that produce the two proteins most vital to skin barrier integrity, filaggrin and claudin, and how they support those proteins being released in the skin barrier.
*PBS refers to a non-irritating salt solution used as a negative control.
THE RESULTS
All Plantkos® formulas tested effective for activating both filaggrin and claudin, and were shown to elevate the skin’s ability to distribute both, resulting in a healthier and stronger skin barrier.
SKIN IRRITATION
THE TEST
The tested products were applied to the skin and then irritation was tested along guidelines established by the OECD to determine toxicity and inflammation.
*PBS refers to a non-irritating salt solution used as a negative control.
THE RESULTS
All Plantkos® formulas were determined not to cause any irritation or inflammation. Each exceeded the testing standard of maintaining 50% skin viability, with an average skin viability of 88.7% - determining that each formula is non-irritating to skin.